ABC transporter expression profiling after ischemic reperfusion injury in mouse kidney
نویسندگان
چکیده
منابع مشابه
Nuclear Magnetic Resonance Metabolomic Profiling of Mouse Kidney, Urine and Serum Following Renal Ischemia/Reperfusion Injury
BACKGROUND Ischemia/reperfusion (I/R) is the most common cause of acute kidney injury (AKI). Its pathophysiology remains unclear. Metabolomics is dedicated to identify metabolites involved in (patho)physiological changes of integrated living systems. Here, we performed 1H-Nuclear Magnetic Resonance metabolomics using urine, serum and kidney samples from a mouse model of renal I/R. METHODS Ren...
متن کاملIschemic preconditioning in hepatic ischemic-reperfusion injury
http://dx.doi.org/10.1016/j.fjs.2016. 1682-606X/Copyright a 2016, Taiwan S NC-ND license (http://creativecommo Abstract Background/Introduction: Ischemic preconditioning is a method in which brief periods of ischemia render tissues resistant to injury resulting from prolonged ischemia and reperfusion, so-called ischemiaereperfusion injury. Purpose: To elucidate the possible protective role of i...
متن کاملReduction in ischemic brain injury following the administration of pentoxifylline after transient global ischemia/ reperfusion in a rat model
Background: It is well known that the hippocampus, the CA1 Pyramidal cells in particular, is selectively vulnerable during global cerebral ischemia. Recently, it is observed that pentoxifylline has a neuroprotective effect. This study explored the pharmacological relationship between ischemia-induced cell death of the hippocampus and the efficacy of a vasodilator agent (pentoxifylline) in the...
متن کاملIschemic and Reperfusion Injury
The study 1 published in this issue of Circulation Research showing that a null mutation of NHE-1 improves the tolerance of the heart to ischemia and reperfusion (I/R) is an important contribution for the following reasons: (1) In the animals with null mutation, contracture during the ischemic period was less and ATP levels were preserved compared with wild-type animals. This observation, on th...
متن کاملthe effect of pentoxifylline drug on bax/bcl2 gene dosage expression changes following ischemic reperfusion injury in kidney
global cerebral ischemia (gci) and reperfusion induced apoptosis that lead to cell injury and death. the bax and bcl-2 are pro-apoptotic and anti-apoptotic genes, respectively. these genes belong to the b-cell lymphoma-2 (bcl-2) family.in this study; we assessed the effect of pentoxifylline drug on bax/bcl2 gene dosage expression changes following ischemic reperfusion injury in kidney. in thi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Kidney International
سال: 2006
ISSN: 0085-2538
DOI: 10.1038/sj.ki.5000407